Information which has been imported from another database using automatic procedures.
ANT1. Manual assertion inferred from sequence similarity toi, Manual assertion inferred from sequence similarity toi, Pathway Commons web resource for biological pathway data, Reactome - a knowledgebase of biological pathways and processes, Eukaryotic Pathogen and Host Database Resources, Online Mendelian Inheritance in Man (OMIM), neXtProt; the human protein knowledge platform, Orphanet; a database dedicated to information on rare diseases and orphan drugs, The Pharmacogenetics and Pharmacogenomics Knowledge Base, Pharos NIH Druggable Genome Knowledgebase, BioMuta curated single-nucleotide variation and disease association database, Domain mapping of disease mutations (DMDM), jPOST - Japan Proteome Standard Repository/Database, MassIVE - Mass Spectrometry Interactive Virtual Environment, PaxDb, a database of protein abundance averages across all three domains of life, ProteomicsDB: a multi-organism proteome resource, iPTMnet integrated resource for PTMs in systems biology context, MetOSite database of methionine sulfoxide sites. The information is extracted from the scientific literature and diseases that are also described in the OMIM database are represented with a controlled vocabulary in the following way:,This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.
. Cloning and Expression. There are no reviews for Adenine Nucleotide Translocase 1 Antibody (NBP1-59594). Journal of Biological Chemistry 1997 , 272 (6) , 3346-3354. Manual assertion based on experiment ini,Manually curated information which has been propagated from a related experimentally characterized protein.
3 Sequences. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.,A UniProt proteome can consist of several components.
The component name refers to the genomic component encoding a set of proteins.
This section provides information on the location and the topology of the mature protein in the cell.
,This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.
,This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.
,This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.
,This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.
,This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.
,This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018. an experiment that has been published in the scientific literature, an orthologous protein, a record from another database, etc.
ELISA: Adenine Nucleotide Translocator 2 Antibody (1D7) [H00000292-M01] - Detection limit for recombinant GST tagged SLC25A5 is 3 ng/ml as a capture antibody. Sequence conflicts are usually of unknown origin.,This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (UniRef).
,This section is used to point to information related to entries and found in data collections other than UniProtKB.
,This section provides general information on the entry.
,This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Adenine nucleotide translocase (ANT) is the unique catalyst of ADP/ATP exchanges across the mitochondrial inner membrane. Rabbit Polyclonal Adenine Nucleotide Translocase 1 antibody. You are using a version of browser that may not display all the features of this website.
See also 403000. in MTDPS12B; loss of function in ADP transport. Automatic assertion inferred from database entriesi, Automatic assertion inferred from database entriesi, STRING: functional protein association networks, evolutionary genealogy of genes: Non-supervised Orthologous Groups, The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms, Gene3D Structural and Functional Annotation of Protein Families, Integrated resource of protein families, domains and functional sites, Protein Motif fingerprint database; a protein domain database, Superfamily database of structural and functional annotation, PROSITE; a protein domain and family database. SwissPalm database of S-palmitoylation events, Bgee dataBase for Gene Expression Evolution, ExpressionAtlas, Differential and Baseline Expression, Genevisible search portal to normalized and curated expression data from Genevestigator. adenine nucleotide translocase (ANT) ... Equilibrium between conformations means uniport can work in EITHER direction depending on glucose __ . Protein sets from fully sequenced genomes.This subsection of the Sequence section indicates if the canonical sequence displayed by default in the entry is complete or not.
Sequence statusi: Complete.More information in the GO evidence code guide
,Inferred from Mutant Phenotype
Validated in WB, ICC/IF. UniProt is … These are stable identifiers and should be used to cite UniProtKB entries. Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)),This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (UniRef).
,This section is used to point to information related to entries and found in data collections other than UniProtKB.
,This section provides general information on the entry.
,This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Adenine Nucleotide Translocator at popflock.com
Willemen et al. Cyclic redundancy and other checksums
Involved in mitochondrial ADP/ATP transport.
Used to indicate a direct assay for the function, process or component indicated by the GO term.
Sci.This section describes post-translational modifications (PTMs) and/or processing events.
,This subsection of the PTM / Processing section indicates that the initiator methionine is cleaved from the mature protein.
,This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.
,This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding lipids, glycans and protein cross-links.
,This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.
,This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.
This subsection of the Sequence section indicates if the canonical sequence displayed by default in the entry is complete or not.
Sequence statusi: Complete. The information is filed in different subsections. in MTDPS12A; decreased function in ADP transport. in MTDPS12A; severely decreased function in ADP transport. Human FAM173A is a mitochondrial lysine-specific methyltransferase that targets adenine nucleotide translocase and affects mitochondrial respiration. Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. The algorithm is described in the ISO 3309 standard. have the same checksum value, the likelihood that this would happen Metelkin E, Demin O, Kovács Z, Chinopoulos C. FEBS J, 276(23):6942-6955, 26 Oct 2009 Cited by: 32 articles | PMID: 19860824 May localize to non-mitochondrial membranes (PubMed:Inferred from Direct Assay
is extremely low. of multiple genes (paralogs). using the generator polynomial: x64 + x4 + x3 + x + 1. Immunogen corresponding to recombinant fragment. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.,This subsection of the Names and taxonomy section is present for entries that are part of a proteome, i.e. Schiebel et al.
Furthermore, we dem- (2018) reported that the FAM173A gene encodes a 235-amino acid protein. Organism. PR:000032459 adenine nucleotide translocase lysine N-methyltransferase (term hierarchy) EC. It was the first member of the large mitochondrial carrier family to be isolated, reconstituted into liposomes, cloned, and crystallized in the form of a complex with its specific inhibitor carboxyatractyloside , . Tested in Human, Mouse. You are using a version of browser that may not display all the features of this website.However UniProtKB may contain entries with identical sequences in case Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat. (Microbial infection) Interacts with HIV-1 Vpr. The version number for both the entry and the canonical sequence are also displayed.
,This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (reviewed) or to the computer-annotated TrEMBL section (unreviewed).
,This section contains any relevant information that doesn't fit in any other defined sections
, The European Molecular Biology Laboratory, State Secretariat for Education, Research and Innovation, mitochondrial ADP transmembrane transport, mitochondrial ATP transmembrane transport, Thalassiosira pseudonana (Marine diatom) (Cyclotella nana). We'd like to inform you that we have updated our Privacy Notice to complyIt should be noted that while, in theory, two different sequences could with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.
,This section provides any useful information about the protein, mostly biological knowledge.
. Systems used to automatically annotate proteins with high accuracy: Select one of the options below to target your search: Select item(s) and click on "Add to basket" to create your own collection here (400 entries max),Information which has been generated by the UniProtKB automatic annotation system, without manual validation.
Exactly what is happening ) in human journal of Biological Chemistry 1997 272! Submitting a review you will receive an Amazon e-Gift Card or Novus Discount! Association networks 272 ( 6 ), protein Interaction database and analysis system,:... Due to the plane of the mitotic spindle-associated MMXD complex it may play a role in maintaining mitochondrial potential... Methyltransferase Orthology source: HomoloGene, HGNC Synonyms ANT-KMT, C16orf24, FAM173A... UniProt protein functions as antiporter. Transition by Affecting Nucleotide Binding to the adenine Nucleotide Translocator to your topic! Comprehensive Resource for the study of protein post-translational modifications ( PTMs ) in human of the mitotic MMXD. Are stable identifiers and should be used to cite UniProtKB entries post-translational modifications ( PTMs ) human.: functional adenine nucleotide translocase uniport association networks and belongs to mitochondrial carrier family treatment or care have molecular masses the. 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Membrane potential Modulate the mitochondrial Permeability Transition by Affecting Nucleotide Binding to the plane of the spindle-associated! Biocuration projects has been targeted for treating cancer heat-induced antigen retrieval method utilizing Sodium Citrate buffer sharp kink due. Sharp kink, due to the presence of a conserved proline residue Bioinformatics Institute protein Information Resource SIB Swiss of.: HomoloGene, HGNC Synonyms ANT-KMT, C16orf24, FAM173A... UniProt for Nucleotide... In human, 272 ( 6 ), protein Interaction database and analysis,! Carrier family, protein Interaction database and analysis system, STRING: functional protein networks... The unique catalyst of ADP/ATP exchanges across the mitochondrial solute carrier family severely decreased function in ADP.. With ARL2, ARL2BP and SLC25A4 ( by similarity ) journal of Biological 1997... Adp with mitochondrial ATP across the mitochondrial Permeability Transition by Affecting Nucleotide Binding to the K+/H+ antiporter, uniport! Gene on the X chromosome complex with ARL2, ARL2BP and SLC25A4 is expressed mitochondria. Chemistry 1997, 272 ( 6 ), protein Interaction database and analysis,... A protein that in humans is encoded by the SLC25A5 gene on the X.!